HIROTA, Morihiko: search on Z-Library

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1

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

Yuko Nukada, Takao Ashikaga, Masaaki Miyazawa, Morihiko Hirota, Hitoshi Sakaguchi, Hitoshi Sasa, Naohiro Nishiyama

Journal:

Toxicology in Vitro

Year:

2012

Language:

english

File:

PDF, 555 KB

english, 2012

2

Oxidation of Cell Surface Thiol Groups by Contact Sensitizers Triggers the Maturation of Dendritic Cells

Kagatani, Saori, Sasaki, Yoshinori, Hirota, Morihiko, Mizuashi, Masato, Suzuki, Mie, Ohtani, Tomoyuki, Itagaki, Hiroshi, Aiba, Setsuya

Journal:

The Journal of Investigative Dermatology

Year:

2010

Language:

english

File:

PDF, 1.66 MB

english, 2010

3

Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization

Hirota, Morihiko, Fukui, Shiho, Okamoto, Kenji, Kurotani, Satoru, Imai, Noriyasu, Fujishiro, Miyuki, Kyotani, Daiki, Kato, Yoshinao, Kasahara, Toshihiko, Fujita, Masaharu, Toyoda, Akemi, Sekiya, Daisu

Journal:

Journal of Applied Toxicology

Year:

2015

Language:

english

File:

PDF, 4.62 MB

english, 2015

4

Non-animal photosafety assessment approaches for cosmetics based on the photochemical and photobiochemical properties

Onoue, Satomi, Suzuki, Gen, Kato, Masashi, Hirota, Morihiko, Nishida, Hayato, Kitagaki, Masato, Kouzuki, Hirokazu, Yamada, Shizuo

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

5

Development of an in vitro photosensitization assay using human monocyte-derived cells

Masatoshi Hoya, Morihiko Hirota, Mie Suzuki, Shigenobu Hagino, Hiroshi Itagaki, Setsuya Aiba

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 417 KB

english, 2009

6

Development of novel in vitro photosafety assays focused on the Keap1-Nrf2-ARE pathway

Tsujita-Inoue, Kyoko, Hirota, Morihiko, Atobe, Tomomi, Ashikaga, Takao, Tokura, Yoshiki, Kouzuki, Hirokazu

Journal:

Journal of Applied Toxicology

Year:

2016

Language:

english

File:

PDF, 2.26 MB

english, 2016

7

In silico risk assessment for skin sensitization using artificial neural network analysis

Tsujita-Inoue, Kyoko, Atobe, Tomomi, Hirota, Morihiko, Ashikaga, Takao, Kouzuki, Hirokazu

Journal:

The Journal of Toxicological Sciences

Year:

2015

Language:

english

File:

PDF, 447 KB

english, 2015

8

Comparative study on prediction performance of photosafety testing tools on photoallergens

Onoue, Satomi, Ohtake, Hiroto, Suzuki, Gen, Seto, Yoshiki, Nishida, Hayato, Hirota, Morihiko, Ashikaga, Takao, Kouzuki, Hirokazu

Journal:

Toxicology in Vitro

Year:

2016

Language:

english

File:

PDF, 446 KB

english, 2016

9

Development of an in vitro photosensitization test based on changes of cell-surface thiols and amines as biomarkers: the photo-SH/NH2 test

Oeda, Shiho, Hirota, Morihiko, Nishida, Hayato, Ashikaga, Takao, Sasa, Hitoshi, Aiba, Setsuya, Tokura, Yoshiki, Kouzuki, Hirokazu

Journal:

The Journal of Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 972 KB

english, 2016

10

Development of an artificial neural network model for risk assessment of skin sensitization using human cell line activation test, direct peptide reactivity assay, KeratinoSens™ and in silico structure alert parameter

Hirota, Morihiko, Ashikaga, Takao, Kouzuki, Hirokazu

Journal:

Journal of Applied Toxicology

Year:

2017

Language:

english

File:

PDF, 562 KB

english, 2017

11

Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)

Yuko Nukada, Takao Ashikaga, Hitoshi Sakaguchi, Sakiko Sono, Nanae Mugita, Morihiko Hirota, Masaaki Miyazawa, Yuichi Ito, Hitoshi Sasa, Naohiro Nishiyama

Journal:

Contact Dermatitis

Year:

2011

Language:

english

File:

PDF, 518 KB

english, 2011

12

SIRC-CVS CYTOTOXICITY TEST: AN ALTERNATIVE FOR PREDICTING RODENT ACUTE SYSTEMIC TOXICITY

KITAGAKI, Masato, WAKURI, Shinobu, HIROTA, Morihiko, TANAKA, Noriho, ITAGAKI, Hiroshi

Journal:

The Journal of Toxicological Sciences

Year:

2006

Language:

english

File:

PDF, 140 KB

english, 2006

13

Evaluation of changes of cell-surface thiols as a new biomarker for in vitro sensitization test

Mie Suzuki, Morihiko Hirota, Shigenobu Hagino, Hiroshi Itagaki, Setsuya Aiba

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 672 KB

english, 2009

14

Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools

Nishida, Hayato, Hirota, Morihiko, Seto, Yoshiki, Suzuki, Gen, Kato, Masashi, Kitagaki, Masato, Sugiyama, Mariko, Kouzuki, Hirokazu, Onoue, Satomi

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

15

Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: Possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate

Hirota, Morihiko, Suzuki, Mie, Hagino, Shigenobu, Kagatani, Saori, Sasaki, Yoshinori, Aiba, Setsuya, Itagaki, Hiroshi

Journal:

The Journal of Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

16

Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients

Gilmour, Nicola, Kern, Petra S., AlÃ©pÃ©e, Nathalie, BoislÃ¨ve, Fanny, Bury, Dagmar, Clouet, Elodie, Hirota, Morihiko, Hoffmann, Sebastian, KÃ¼hnl, Jochen, Lalko, Jon F., Mewes, Karsten, Miyazawa, Mas

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 2.26 MB

2020

17

Nucleotide Sequences and Organization of the Genes for Carotovoricin (Ctv) from Erwinia carotovora Indicate That Ctv Evolved from the Same Ancestor as Salmonella typhi Prophage

YAMADA, Kazuteru, HIROTA, Morihiko, NIIMI, Yoshiko, NGUYEN, Hoa Anh, TAKAHARA, Yoshiyuki, KAMIO, Yoshiyuki, KANEKO, Jun

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

18

MIP-1β, a novel biomarker for in vitro sensitization test using human monocytic cell line

Morihiko Hirota, Osamu Moro

Journal:

Toxicology in Vitro

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

19

Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone

Hirota, Morihiko, Motoyama, Akira, Suzuki, Mie, Yanagi, Masashi, Kitagaki, Masato, Kouzuki, Hirokazu, Hagino, Shigenobu, Itagaki, Hiroshi, Sasa, Hitoshi, Kagatani, Saori, Aiba, Setsuya

Journal:

The Journal of Toxicological Sciences

Year:

2010

Language:

english

File:

PDF, 642 KB

english, 2010

20

Skin sensitization risk assessment model using artificial neural network analysis of data from multiple in vitro assays

Tsujita-Inoue, Kyoko, Hirota, Morihiko, Ashikaga, Takao, Atobe, Tomomi, Kouzuki, Hirokazu, Aiba, Setsuya

Journal:

Toxicology in Vitro

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

21

Integration of read-across and artificial neural network-based QSAR models for predicting systemic toxicity: A case study for valproic acid

Hisaki, Tomoka, Kaneko, Maki Aiba nÃ©e, Hirota, Morihiko, Matsuoka, Masato, Kouzuki, Hirokazu

Journal:

The Journal of Toxicological Sciences

Year:

2020

Language:

english

File:

PDF, 1.23 MB

english, 2020

22

QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS

HIROTA, Morihiko, KITAGAKI, Masato, ITAGAKI, Hiroshi, AIBA, Setsuya

Journal:

The Journal of Toxicological Sciences

Year:

2006

Language:

english

File:

PDF, 583 KB

english, 2006

23

Prediction of genotoxic potential of cosmetic ingredients by an in silico battery system consisting of a combination of an expert rule-based system and a statistics-based system

Aiba née Kaneko, Maki, Hirota, Morihiko, Kouzuki, Hirokazu, Mori, Masaaki

Journal:

The Journal of Toxicological Sciences

Year:

2015

Language:

english

File:

PDF, 303 KB

english, 2015

24

A Simple Purification Method and Morphology and Component Analyses for Carotovoricin Er, a Phage-tail-like Bacteriocin from the Plant Pathogen Erwinia carotovora Er

NGUYEN, Anh Hoa, TOMITA, Toshio, HIROTA, Morihiko, SATO, Tsuruji, KAMIO, Yoshiyuki

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1999

File:

PDF, 5.16 MB

1999

25

Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments

Onoue, Satomi, Seto, Yoshiki, Sato, Hideyuki, Nishida, Hayato, Hirota, Morihiko, Ashikaga, Takao, Api, Anne Marie, Basketter, David, Tokura, Yoshiki

Journal:

Journal of Dermatological Science

Year:

2016

Language:

english

File:

PDF, 866 KB

english, 2016

26

Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals

Hirota, Morihiko, Kouzuki, Hirokazu, Ashikaga, Takao, Sono, Sakiko, Tsujita, Kyoko, Sasa, Hitoshi, Aiba, Setsuya

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

27

Mechanism-based integrated assay systems for the prediction of drug-induced liver injury

Kawaguchi, Moemi, Nukaga, Takumi, Sekine, Shuichi, Takemura, Akinori, Susukida, Takeshi, Oeda, Shiho, Kodama, Atsushi, Hirota, Morihiko, Kouzuki, Hirokazu, Ito, Kousei

Journal:

Toxicology and Applied Pharmacology

Year:

2020

File:

PDF, 1.84 MB

2020

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